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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
12.12
Human Site:
S1292
Identified Species:
20.51
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1292
P
R
P
P
R
P
P
S
P
P
P
E
P
E
T
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1125
P
A
G
P
T
E
E
S
P
P
S
V
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
A59
N
N
A
S
P
D
R
A
R
P
D
S
Q
F
P
Dog
Lupus familis
XP_543382
1925
209302
S1294
P
R
P
P
R
P
P
S
P
P
P
E
P
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1354
P
R
L
L
R
P
P
S
P
P
P
E
P
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
G130
T
D
M
C
K
K
Y
G
E
V
E
E
V
E
I
Chicken
Gallus gallus
Q5F3P8
2008
223067
P1364
G
K
E
E
S
V
V
P
P
E
K
F
P
E
Q
Frog
Xenopus laevis
Q66J90
1938
216239
C1312
S
H
N
K
E
E
E
C
L
L
P
P
E
K
H
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
Q1235
P
S
H
V
P
D
P
Q
S
L
L
P
P
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
D1075
E
E
I
K
K
K
V
D
C
K
Q
K
P
S
F
Honey Bee
Apis mellifera
XP_395451
1406
159180
E841
V
L
S
P
L
E
Y
E
S
D
K
E
D
N
E
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
F942
K
R
R
R
R
A
S
F
S
S
T
S
I
Q
S
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1222
L
M
A
K
A
K
V
S
P
P
K
E
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
S748
N
S
D
S
D
D
D
S
D
D
G
V
D
N
R
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
40
6.6
93.3
N.A.
86.6
N.A.
N.A.
13.3
20
6.6
20
N.A.
6.6
13.3
13.3
33.3
P-Site Similarity:
100
40
13.3
100
N.A.
86.6
N.A.
N.A.
20
26.6
13.3
20
N.A.
20
13.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
8
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
22
8
8
8
15
8
0
15
8
0
% D
% Glu:
8
8
8
8
8
22
15
8
8
8
8
43
15
36
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% F
% Gly:
8
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
8
8
0
22
15
22
0
0
0
8
22
8
0
8
8
% K
% Leu:
8
8
8
8
8
0
0
0
8
15
8
0
0
8
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
8
0
0
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
36
0
15
29
15
22
29
8
43
43
29
15
50
8
15
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
0
8
8
8
% Q
% Arg:
0
29
8
8
29
0
8
0
8
0
0
0
0
0
8
% R
% Ser:
8
15
8
15
8
0
8
43
22
8
8
15
0
8
8
% S
% Thr:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
22
% T
% Val:
8
0
0
8
0
8
22
0
0
8
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _